Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30140249 | 1.00 | GPR119 (0.49) | GPR119USP30PIK3CDPIK3CAALK | |
| SCHEMBL30140200 | 0.84 | GPR119 (0.42) | GPR119USP30PIK3CDPIK3CAPIK3CB | |
| SCHEMBL29025864 | 0.81 | RET (0.46) | GPR119 | |
| SCHEMBL30127474 | 0.81 | PDE4B (0.44) | GPR119USP30PIK3CD | |
| SCHEMBL30126023 | 0.81 | PDE4B (0.44) | GPR119USP30PIK3CD | |
| SCHEMBL30126772 | 0.81 | PDE4B (0.44) | GPR119USP30PIK3CD | |
| SCHEMBL30140095 | 0.81 | GPR119 (0.56) | GPR119USP30PIK3CDPIK3CAALK | |
| SCHEMBL21887529 | 0.79 | GPR119 (0.56) | GPR119USP30ALKTBK1 | |
| SCHEMBL30140067 | 0.79 | PIK3CD (0.43) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL27108934 | 0.79 | GPR119 (0.53) | GPR119USP30PIK3CDPIK3CAALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266426-A1 | 6-(HETEROCYCLOALKYL-OXY)-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |