Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13419621 | 1.00 | GPR119 (0.57) | GPR119ALDH1A1LMNAMAPTPDE4B | |
| SCHEMBL13419624 | 0.94 | GPR119 (0.51) | GPR119ALDH1A1LMNAMAPTPDE4B | |
| SCHEMBL31216608 | 0.94 | GPR119 (0.64) | GPR119ALDH1A1LMNAMAPTPDE4B | |
| SCHEMBL31216598 | 0.94 | GPR119 (0.64) | GPR119ALDH1A1LMNAMAPTPDE4B | |
| SCHEMBL2255441 | 0.94 | GPR119 (0.64) | GPR119ALDH1A1LMNAMAPTPDE4B | |
| SCHEMBL16980642 | 0.92 | GPR119 (0.50) | GPR119ALDH1A1LMNAMAPTPDE4B | |
| SCHEMBL16980512 | 0.92 | GPR119 (0.50) | GPR119ALDH1A1LMNAMAPTPDE4B | |
| SCHEMBL12002916 | 0.92 | GPR119 (0.51) | GPR119ALDH1A1LMNAMAPTPDE4B | |
| SCHEMBL30912375 | 0.89 | ALDH1A1 (0.49) | GPR119ALDH1A1LMNAMAPTPDE4B | |
| SCHEMBL30962804 | 0.89 | ALDH1A1 (0.49) | GPR119ALDH1A1LMNAMAPTPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266426-A1 | 6-(HETEROCYCLOALKYL-OXY)-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |