⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28695900 | 0.97 | TSHR (0.48) | — | |
| SCHEMBL31338794 | 0.97 | TSHR (0.48) | — | |
| SCHEMBL20725833 | 0.97 | TSHR (0.48) | — | |
| SCHEMBL5495726 | 0.97 | TSHR (0.48) | — | |
| SCHEMBL9787863 | 0.97 | TSHR (0.48) | — | |
| SCHEMBL25252646 | 0.97 | TSHR (0.48) | — | |
| SCHEMBL196200 | 0.97 | TSHR (0.48) | — | |
| SCHEMBL22263515 | 0.97 | TSHR (0.48) | — | |
| SCHEMBL663207 | 0.97 | TSHR (0.48) | — | |
| SCHEMBL15638673 | 0.97 | TSHR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166149-B | Compounds for the treatment of type II diabetes | 尼奥比奥特克有限责任公司 | 2024-02-23 | — | — | CN | claimed |
| EP-3860989-B1 | FUSED PYRROLINES WHICH ACT AS UBIQUITIN-SPECIFIC PROTEASE 30 (USP30) INHIBITORS | FORMA THERAPEUTICS INC (US) | 2023-04-05 | — | — | EP | claimed |
| CN-114269323-A | Hydrophilic linkers for multivalent peptide conjugates | 瓦利托尔有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-113166149-A | Compounds for the treatment of type II diabetes | 尼奥比奥特克有限责任公司 | 2021-07-23 | — | — | CN | claimed |
| US-20200291355-A1 | ENGINEERED ERYTHROID CELLS INCLUDING LOADABLE ANTIGEN-PRESENTING POLYPEPTIDES AND METHODS OF USE | RUBIUS THERAPEUTICS, INC. | 2020-09-17 | — | — | US | claimed |
| CN-111378137-A | Force-induced responsive polymer with multi-network structure | 翁秋梅 | 2020-07-07 | — | — | CN | claimed |
| CN-107137387-B | Synthetic method of aryl propionic acid non-steroidal anti-inflammatory drug | 中国科学技术大学 | 2020-05-12 | — | — | CN | claimed |
| CN-111093712-A | Bioconjugates with controlled degree of conjugation, process for their preparation and reagents for their preparation | 国家科学研究中心 | 2020-05-01 | — | — | CN | claimed |
| CN-111040204-A | Force-induced response dynamic polymer and application thereof | 翁秋梅 | 2020-04-21 | — | — | CN | claimed |
| CN-111040110-A | Force-induced response dynamic polymer and application thereof | 翁秋梅 | 2020-04-21 | — | — | CN | claimed |
| WO-2020067930-A1 | COMPOUNDS FOR TREATING TYPE 2 DIABETES | Общество с ограниченной ответственностью "Необиотек" | 2020-04-02 | — | — | WO | claimed |
| EP-3085703-A1 | Use of thiol-containing scavengers for purification of antibody-drug conjugates | Lonza Ltd (CH) | 2016-10-26 | — | — | EP | claimed |
| WO-2008077809-A1 | PROCESS FOR THE MANUFACTURE OF 7-OXA-BICYCLO DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-07-03 | — | — | WO | claimed |
| US-20030049807-A1 | Micro-organism possessing enantioselective and regioselective nitrile hydratase/amidase activities | INSTITUTO BIOCHIMICO ITALIANO GIOVANNI LOREZINI S.P.A. (IT) | 2003-03-13 | — | — | US | claimed |
| EP-1291435-A2 | A micro-organism possessing enantioselective and regioselective nitrile hydratase/amidase activities | ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.p.A. (IT) | 2003-03-12 | — | — | EP | claimed |
| EP-0330529-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 2-ARYL-PROPIONIC ACIDS | RHONE-POULENC SANTE (FR) | 1993-03-31 | — | — | EP | claimed |
| US-5089405-A | Hydrolysis of racemic 2-arylpropionamides | RHONE-POULENC SANTE (FR) | 1992-02-18 | — | — | US | claimed |
| JP-61165358-A | — | — | None | — | — | JP | disclosed |
| US-3948858-A | INITIATOR OF 1,2-DIARYL-1,2-CYANO-1,2-DIHALOETHANE | AKZO N.V. (NL) | 1976-04-06 | — | — | US | disclosed |
| US-3932678-A | Novel dihydrochalcone sweetener compositions | THE PROCTER & GAMBLE COMPANY (US) | 1976-01-13 | — | — | US | disclosed |