Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA2 | P16389 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.66 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | BACE1 | P56817 | 3/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SI | P14410 | 2/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31315053 | 0.81 | CYP1B1 (0.88) | KCNA2KDM4ECYP1A1CYP3A4CYP1A2 | |
| SCHEMBL4261444 | 0.81 | KCNA2 (0.67) | KCNA2KDM4ECYP1A1CYP3A4CYP1A2 | |
| Isopimpinellin SCHEMBL498907 | 0.80 | CYP3A4 (1.00) | KCNA2KDM4ECYP1A1CYP3A4CYP1A2 | |
| Isopimpinellin SCHEMBL29568822 | 0.80 | CYP3A4 (1.00) | KCNA2KDM4ECYP1A1CYP3A4CYP1A2 | |
| SCHEMBL9122678 | 0.78 | ALDH1A1 (0.71) | KCNA2KDM4ECYP1A1CYP3A4CYP1A2 | |
| SCHEMBL8806449 | 0.78 | CYP3A4 (0.71) | KCNA2KDM4ECYP3A4CYP1A2CYP1B1 | |
| SCHEMBL4268685 | 0.76 | KCNA2 (0.60) | KCNA2KDM4ECYP1A1CYP3A4CYP1A2 | |
| Byakangelicol SCHEMBL28985145 | 0.75 | KDM4E (0.67) | KCNA2KDM4ECYP1A1CYP3A4CYP1A2 | |
| Byakangelicol SCHEMBL21986509 | 0.75 | KDM4E (0.67) | KCNA2KDM4ECYP1A1CYP3A4CYP1A2 | |
| Phellopterin SCHEMBL2468854 | 0.75 | CYP1B1 (1.00) | KCNA2KDM4ECYP1A1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100191475-A1 | METHOD FOR IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION OF AGENTS WHICH MODULATE ION CHANNEL ACTIVITY | PERSCHKE SCOTT | 2010-07-29 | — | — | US | disclosed |
| EP-1839222-A2 | A METHOD FOR IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION OF AGENTS WHICH MODULATE ION CHANNEL ACTIVITY | Novascreen Biosciences (US) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006066219-A2 | A METHOD FOR IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION OF AGENTS WHICH MODULATE ION CHANNEL ACTIVITY | NOVASCREEN BIOSCIENCES (US) | 2006-06-22 | — | — | WO | disclosed |
| US-20060136140-A1 | Method for identification and functional characterization of agents which modulate ion channel activity | NOVASCREEN BIOSCIENCES | 2006-06-22 | — | — | US | disclosed |