Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 1/20 | 0.49 |
| ▸ | P2RY2 | P41231 | 11/20 | 0.48 |
| ▸ | P2RY4 | P51582 | 6/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28633711 | 0.89 | P2RY2 (0.44) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL28518605 | 0.89 | POLG (0.47) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL10903450 | 0.88 | POLG (0.45) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL3635669 | 0.88 | POLG (0.46) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL18394211 | 0.87 | P2RY2 (0.51) | POLGP2RY2P2RY4P2RY6POLB | |
| Guanidine SCHEMBL28645150 | 0.86 | P2RY2 (0.42) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL26102705 | 0.86 | POLG (0.51) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL31337304 | 0.86 | POLG (0.47) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL30697338 | 0.85 | P2RY2 (0.51) | POLGP2RY2P2RY4P2RY6 | |
| SCHEMBL4254632 | 0.82 | POLG (0.49) | POLGP2RY2P2RY4P2RY6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022269346-A2 | COMPOSITIONS AND METHODS OF MODULATING XANTHINE DEHYDROGENASE | HORIZON THERAPEUTICS IRELAND DAC (IE) | 2022-12-29 | — | — | WO | disclosed |