SCHEMBL30697338

SCHEMBL30697338

CO[C@@]1(n2ccc(N)nc2=O)O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.63

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 13/20 0.51
POLG P54098 1/20 0.49
P2RY4 P51582 7/20 0.46
P2RY6 Q15077 7/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31337304 0.91 POLG (0.47) P2RY2POLGP2RY4P2RY6
SCHEMBL18394211 0.87 P2RY2 (0.51) P2RY2POLGP2RY4P2RY6
SCHEMBL26102705 0.86 POLG (0.51) P2RY2POLGP2RY4P2RY6
SCHEMBL30140872 0.85 POLG (0.49) P2RY2POLGP2RY4P2RY6
SCHEMBL4254632 0.82 POLG (0.49) P2RY2POLGP2RY4P2RY6
SCHEMBL30697340 0.81 P2RY2 (0.58) P2RY2P2RY4P2RY6
SCHEMBL28518605 0.81 POLG (0.47) P2RY2POLGP2RY4P2RY6
SCHEMBL3635669 0.81 POLG (0.46) P2RY2POLGP2RY4P2RY6
SCHEMBL10903450 0.81 POLG (0.45) P2RY2POLGP2RY4P2RY6
SCHEMBL24309037 0.80 POLG (0.51) P2RY2POLGP2RY4P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119080855-A Chemically modified cytosine nucleoside triphosphate and preparation method and application thereof 中国科学院深圳先进技术研究院 2024-12-06 CN disclosed
CN-117247932-A Method for improving utilization rate of cap analogues in-vitro transcription 南京诺唯赞生物科技股份有限公司 2023-12-19 CN disclosed