Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 5/20 | 0.45 |
| ▸ | NT5E | P21589 | 5/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | AHCY | P23526 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608943 | 0.86 | TYMP (0.59) | TYMPNT5ECA5AADORA1AHCY | |
| SCHEMBL7607071 | 0.86 | TYMP (0.59) | TYMPNT5ECA5AADORA1AHCY | |
| SCHEMBL30140969 | 0.85 | TYMP (0.50) | TYMPNT5EADORA1 | |
| SCHEMBL30140966 | 0.85 | TYMP (0.50) | TYMPNT5ECA5AADORA1ADORA2A | |
| SCHEMBL30141046 | 0.82 | TYMP (0.47) | TYMPNT5ECA5AADORA1 | |
| SCHEMBL30140976 | 0.82 | TYMP (0.47) | TYMPNT5ECA5AADORA1 | |
| SCHEMBL4827218 | 0.82 | TYMP (0.45) | TYMPADORA1ADORA2A | |
| SCHEMBL5133061 | 0.81 | KDM4E (0.53) | TYMPNT5E | |
| SCHEMBL14049947 | 0.81 | TYMP (0.44) | TYMPADORA2A | |
| SCHEMBL7882460 | 0.80 | TYMP (0.49) | TYMPNT5EADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4370136-A2 | SIMPLE CHEMICAL APPROACHES TO INTRODUCE 2,6-DIAMINOPURINE AND 2-AMINOADENINE CONJUGATES INTO OLIGONUCLEOTIDES | Alnylam Pharmaceuticals, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| WO-2023288045-A2 | SIMPLE CHEMICAL APPROACHES TO INTRODUCE 2,6-DIAMINOPURINE AND 2-AMINOADENINE CONJUGATES INTO OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |