Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.78 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.78 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.75 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.75 |
| ▸ | KDR | P35968 | 5/20 | 0.73 |
| ▸ | RET | P07949 | 2/20 | 0.73 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.72 |
| ▸ | LCK | P06239 | 4/20 | 0.72 |
| ▸ | FLT3 | P36888 | 2/20 | 0.69 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.69 |
| ▸ | ROS1 | P08922 | 1/20 | 0.69 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.69 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.69 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.69 |
| ▸ | GAK | O14976 | 1/20 | 0.67 |
| ▸ | STK10 | O94804 | 1/20 | 0.67 |
| ▸ | JAK3 | P52333 | 1/20 | 0.67 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.67 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.67 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242224 | 1.00 | EGFR (0.78) | EGFRERBB2RIPK2EPHB2KDR | |
| Hydrochloric Acid SCHEMBL8809813 | 0.99 | EGFR (0.76) | EGFRERBB2RIPK2EPHB2KDR | |
| SCHEMBL8808387 | 0.95 | EGFR (0.75) | EGFRERBB2RIPK2EPHB2KDR | |
| SCHEMBL30891782 | 0.92 | EGFR (0.83) | EGFRERBB2RIPK2EPHB2KDR | |
| Trifluoroacetic Acid SCHEMBL20494312 | 0.91 | EGFR (0.72) | EGFRERBB2RIPK2EPHB2KDR | |
| SCHEMBL15607659 | 0.91 | EGFR (0.78) | EGFRERBB2RIPK2EPHB2KDR | |
| Hydrochloric Acid SCHEMBL8364042 | 0.91 | EGFR (0.70) | EGFRERBB2RIPK2EPHB2KDR | |
| SCHEMBL1387156 | 0.90 | EGFR (0.75) | EGFRERBB2RIPK2EPHB2KDR | |
| Hydrochloric Acid SCHEMBL8810888 | 0.89 | EGFR (0.68) | EGFRERBB2RIPK2EPHB2ERBB4 | |
| Hydrochloric Acid SCHEMBL8811182 | 0.89 | EGFR (0.76) | EGFRERBB2RIPK2EPHB2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159647-A | Method for producing cardiomyocyte layer, and use thereof | 富士胶片株式会社 | 2024-06-07 | — | — | CN | disclosed |
| US-20240016840-A1 | METHODS AND COMPOSITIONS FOR USE OF THERAPEUTIC T CELLS IN COMBINATION WITH KINASE INHIBITORS | JUNO THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | US | disclosed |
| US-11590167-B2 | Methods and compositions for use of therapeutic T cells in combination with kinase inhibitors | Juno Therapeutic, Inc. (US) | 2023-02-28 | — | — | US | disclosed |
| WO-2023286772-A1 | CARDIOMYOCYTE PRODUCTION METHOD | 三菱ケミカル株式会社 | 2023-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016840-A1 | METHODS AND COMPOSITIONS FOR USE OF THERAPEUTIC T CELLS IN COMBINATION WITH KINASE INHIBITORS | ITK, PBK, BMX | EGFR 37/4885ERBB2 13/4885RIPK2 468/4885 |
| US-11590167-B2 | Methods and compositions for use of therapeutic T cells in combination with kinase inhibitors | ITK, PBK, BMX | EGFR 30/4885ERBB2 11/4885RIPK2 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.