Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.83 |
| ▸ | KDR | P35968 | 7/20 | 0.83 |
| ▸ | RET | P07949 | 5/20 | 0.83 |
| ▸ | LCK | P06239 | 4/20 | 0.81 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.69 |
| ▸ | EPHB2 | P29323 | 2/20 | 0.69 |
| ▸ | GAK | O14976 | 1/20 | 0.67 |
| ▸ | STK10 | O94804 | 1/20 | 0.67 |
| ▸ | FLT3 | P36888 | 1/20 | 0.67 |
| ▸ | JAK3 | P52333 | 1/20 | 0.67 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.67 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.67 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.67 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.67 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.67 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.67 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.67 |
| ▸ | FLT1 | P17948 | 1/20 | 0.67 |
| ▸ | CDK2 | P24941 | 1/20 | 0.67 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30141491 | 0.92 | EGFR (0.78) | EGFRKDRRETLCKRIPK2 | |
| SCHEMBL242224 | 0.92 | EGFR (0.78) | EGFRKDRRETLCKRIPK2 | |
| SCHEMBL8870651 | 0.91 | EGFR (0.81) | EGFRKDRRETLCKEPHB2 | |
| SCHEMBL29515328 | 0.91 | EGFR (1.00) | EGFRKDRRETLCKRIPK2 | |
| SCHEMBL1257431 | 0.91 | EGFR (1.00) | EGFRKDRRETLCKRIPK2 | |
| Hydrochloric Acid SCHEMBL8809813 | 0.91 | EGFR (0.76) | EGFRKDRRETLCKRIPK2 | |
| SCHEMBL1387156 | 0.91 | EGFR (0.75) | EGFRKDRRETLCKRIPK2 | |
| SCHEMBL22367364 | 0.90 | EGFR (0.81) | EGFRKDRRETLCKEPHB2 | |
| SCHEMBL668572 | 0.90 | EGFR (0.81) | EGFRKDRRETLCKEPHB2 | |
| Hydrochloric Acid SCHEMBL5475737 | 0.90 | EGFR (1.00) | EGFRKDRRETLCKRIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | disclosed |