Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.75 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.75 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.75 |
| ▸ | KDR | P35968 | 6/20 | 0.73 |
| ▸ | RET | P07949 | 3/20 | 0.73 |
| ▸ | LCK | P06239 | 4/20 | 0.72 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.71 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.67 |
| ▸ | GAK | O14976 | 1/20 | 0.67 |
| ▸ | STK10 | O94804 | 1/20 | 0.67 |
| ▸ | FLT3 | P36888 | 1/20 | 0.67 |
| ▸ | JAK3 | P52333 | 1/20 | 0.67 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.67 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.67 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.67 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.67 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.67 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.67 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.65 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242224 | 0.95 | EGFR (0.78) | EGFRRIPK2EPHB2KDRRET | |
| SCHEMBL30141491 | 0.95 | EGFR (0.78) | EGFRRIPK2EPHB2KDRRET | |
| Hydrochloric Acid SCHEMBL8809813 | 0.94 | EGFR (0.76) | EGFRRIPK2EPHB2KDRRET | |
| SCHEMBL30891782 | 0.90 | EGFR (0.83) | EGFRRIPK2EPHB2KDRRET | |
| SCHEMBL15607659 | 0.89 | EGFR (0.78) | EGFRRIPK2EPHB2KDRRET | |
| SCHEMBL1387156 | 0.87 | EGFR (0.75) | EGFRRIPK2EPHB2KDRRET | |
| SCHEMBL18158179 | 0.87 | EGFR (0.79) | EGFRRIPK2EPHB2KDRRET | |
| Trifluoroacetic Acid SCHEMBL20494312 | 0.87 | EGFR (0.72) | EGFRRIPK2EPHB2KDRRET | |
| Hydrochloric Acid SCHEMBL8811182 | 0.86 | EGFR (0.76) | EGFRRIPK2EPHB2KDRRET | |
| Hydrochloric Acid SCHEMBL8364042 | 0.86 | EGFR (0.70) | EGFRRIPK2EPHB2KDRRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782570-A1 | SUBSTITUTED HETEROAROMATIC COMPOUNDS AND THEIR USE IN MEDICINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996009294-A1 | SUBSTITUTED HETEROAROMATIC COMPOUNDS AND THEIR USE IN MEDICINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-03-28 | — | — | WO | disclosed |