Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27243079 | 0.91 | KDM4E (0.33) | MAPTKMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL30141501 | 0.84 | KDM4E (0.36) | MAPTKMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL24758983 | 0.83 | LMNA (0.36) | MAPTKMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL24906359 | 0.83 | KDM4E (0.35) | MAPTKMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL24906441 | 0.83 | ELANE (0.35) | MAPTKMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL24906374 | 0.83 | KMT2A (0.33) | MAPTKMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL30951783 | 0.83 | LMNA (0.33) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL30951782 | 0.83 | LMNA (0.33) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL24906332 | 0.83 | LMNA (0.33) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL24906362 | 0.82 | LMNA (0.32) | MAPTKMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4355733-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022263498-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2022-12-22 | — | — | WO | disclosed |