Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30951783 | 0.93 | LMNA (0.33) | KDM4EALDH1A1HPGDLMNASLC34A1 | |
| SCHEMBL24906332 | 0.93 | LMNA (0.33) | KDM4EALDH1A1HPGDLMNASLC34A1 | |
| SCHEMBL30951782 | 0.93 | LMNA (0.33) | KDM4EALDH1A1HPGDLMNASLC34A1 | |
| SCHEMBL24906284 | 0.90 | KDM4E (0.35) | KDM4EALDH1A1HPGDLMNAPLAT | |
| SCHEMBL30141508 | 0.87 | CHRM2 (0.31) | KDM4ELMNATSHRIDH1 | |
| SCHEMBL30976021 | 0.86 | LMNA (0.36) | KDM4EALDH1A1HPGDLMNAPLAT | |
| SCHEMBL24906342 | 0.85 | LMNA (0.32) | KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL27243079 | 0.84 | KDM4E (0.33) | KDM4EALDH1A1HPGDLMNASLC34A1 | |
| SCHEMBL30141544 | 0.84 | MAPT (0.34) | KDM4EALDH1A1HPGDLMNASLC34A1 | |
| SCHEMBL30975885 | 0.82 | LMNA (0.32) | KDM4EALDH1A1HPGDLMNAPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4355733-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022263498-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2022-12-22 | — | — | WO | disclosed |