SCHEMBL30141763

SCHEMBL30141763

CC(C)(C)c1ccc(C(=O)OCCSCC(NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)cc1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SLC17A5 Q9NRA2 1/20 0.49
▸ MDM4 O15151 2/20 0.48
▸ TP53 P04637 2/20 0.48
▸ TLR2 O60603 2/20 0.47
▸ MDM2 Q00987 2/20 0.43
▸ CASP3 P42574 1/20 0.42
▸ PPARG P37231 3/20 0.41
▸ PPARA Q07869 3/20 0.41
▸ PPARD Q03181 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30141766 0.91 SLC17A5 (0.53) SLC17A5MDM4TP53TLR2MDM2
SCHEMBL31682399 0.85 SLC17A5 (0.53) SLC17A5MDM4TP53TLR2MDM2
SCHEMBL30141774 0.82 SLC17A5 (0.52) SLC17A5MDM4TP53TLR2MDM2
SCHEMBL18708304 0.82 SLC17A5 (0.52) SLC17A5MDM4TP53TLR2MDM2
SCHEMBL31682400 0.81 SLC17A5 (0.53) SLC17A5MDM4TP53TLR2MDM2
SCHEMBL21664276 0.80 SLC17A5 (0.53) SLC17A5MDM4TP53TLR2MDM2
SCHEMBL16801787 0.80 SLC17A5 (0.53) SLC17A5MDM4TP53TLR2MDM2
SCHEMBL31588379 0.79 MDM4 (0.55) SLC17A5MDM4TP53MDM2CASP3
SCHEMBL3725047 0.79 MDM4 (0.55) SLC17A5MDM4TP53MDM2CASP3
SCHEMBL29657386 0.79 MDM4 (0.55) SLC17A5MDM4TP53MDM2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282827-A1 LIPIDATED POLYMYXIN ANALOGUES AUCKLAND UNISERVICES LTD (NZ) 2025-09-11 — — US disclosed
EP-4384533-A1 LIPIDATED POLYMYXIN ANALOGUES Auckland Uniservices Limited (NZ) 2024-06-19 — — EP disclosed
WO-2023017450-A1 LIPIDATED POLYMYXIN ANALOGUES AUCKLAND UNISERVICES LIMITED (NZ) 2023-02-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282827-A1 LIPIDATED POLYMYXIN ANALOGUES PHOSPHO1, PCTP, PTMS SLC17A5 1388/4885MDM4 4349/4885TP53 4782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback