SCHEMBL30141774

SCHEMBL30141774

CCC(=O)OCCSCC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SLC17A5 Q9NRA2 1/20 0.52
▸ TLR2 O60603 2/20 0.49
▸ MDM4 O15151 2/20 0.49
▸ TP53 P04637 2/20 0.49
▸ CASP3 P42574 2/20 0.47
▸ TNF P01375 3/20 0.46
▸ MDM2 Q00987 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18708304 1.00 SLC17A5 (0.52) SLC17A5TLR2MDM4TP53CASP3
SCHEMBL31682400 0.92 SLC17A5 (0.53) SLC17A5TLR2MDM4TP53CASP3
SCHEMBL18689466 0.89 TLR2 (0.57) SLC17A5TLR2MDM4TP53CASP3
SCHEMBL18689465 0.89 TLR2 (0.57) SLC17A5TLR2MDM4TP53CASP3
SCHEMBL30141761 0.89 TLR2 (0.57) SLC17A5TLR2MDM4TP53CASP3
SCHEMBL22636827 0.89 TLR2 (0.57) SLC17A5TLR2MDM4TP53CASP3
SCHEMBL22636832 0.89 TLR2 (0.57) SLC17A5TLR2MDM4TP53CASP3
SCHEMBL22636828 0.89 TLR2 (0.57) SLC17A5TLR2MDM4TP53CASP3
SCHEMBL22636830 0.89 TLR2 (0.57) SLC17A5TLR2MDM4TP53CASP3
SCHEMBL18708299 0.89 TLR2 (0.57) SLC17A5TLR2MDM4TP53CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282827-A1 LIPIDATED POLYMYXIN ANALOGUES AUCKLAND UNISERVICES LTD (NZ) 2025-09-11 — — US disclosed
EP-4384533-A1 LIPIDATED POLYMYXIN ANALOGUES Auckland Uniservices Limited (NZ) 2024-06-19 — — EP disclosed
WO-2023017450-A1 LIPIDATED POLYMYXIN ANALOGUES AUCKLAND UNISERVICES LIMITED (NZ) 2023-02-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282827-A1 LIPIDATED POLYMYXIN ANALOGUES PHOSPHO1, PCTP, PTMS SLC17A5 1388/4885TLR2 31/4885MDM4 4349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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