Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | MST1R | Q04912 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Noroxyhydrastinine SCHEMBL29745981 | 0.81 | KDM4E (1.00) | KDM4EACHEGRM5CYP2D6PARP1 | |
| Noroxyhydrastinine SCHEMBL564339 | 0.81 | KDM4E (1.00) | KDM4EACHEGRM5CYP2D6PARP1 | |
| SCHEMBL28893845 | 0.79 | CA12 (0.56) | KDM4ECA12CA9CLK4NTRK2 | |
| SCHEMBL32666530 | 0.77 | CA12 (0.54) | KDM4ECA12CA9CLK4NTRK2 | |
| SCHEMBL25028954 | 0.77 | KDM4E (0.42) | KDM4ECA12CA9CLK4NTRK2 | |
| SCHEMBL29397030 | 0.77 | KDM4E (0.42) | KDM4ECA12CA9CLK4NTRK2 | |
| SCHEMBL7283744 | 0.73 | KDM4E (0.53) | KDM4EACHEDYRK1BGSK3BALDH1A1 | |
| SCHEMBL1079809 | 0.69 | CLK4 (0.51) | CA12CA9CLK4NTRK2DYRK1B | |
| SCHEMBL15680247 | 0.69 | CA12 (0.47) | ACHECA12CA9CLK4NTRK2 | |
| SCHEMBL10139776 | 0.69 | HTT (0.52) | CA12CA9CLK4NTRK2DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384523-A1 | 2,2-DIFLUORO-5H-[1,3]DIOXOLO[4,5-F]ISOINDOL-7-ONE DERIVATIVES AS PESTICIDES | Syngenta Crop Protection AG (CH) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023017094-A1 | 2,2-DIFLUORO-5H-[1,3]DIOXOLO[4,5-F]ISOINDOL-7-ONE DERIVATIVES AS PESTICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2023-02-16 | — | — | WO | disclosed |