Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 7/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30142490 | 1.00 | ACKR3 (0.45) | ACKR3NAMPTCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL19925902 | 1.00 | ACKR3 (0.45) | ACKR3NAMPTCHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL19926210 | 0.99 | ACKR3 (0.44) | ACKR3NAMPTCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL19926246 | 0.90 | ACKR3 (0.45) | ACKR3NAMPTCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL30142519 | 0.90 | ACKR3 (0.45) | ACKR3NAMPTCHRNB2CHRNB4CHRNA3 | |
| Bromide SCHEMBL19926355 | 0.89 | ACKR3 (0.44) | ACKR3NAMPTCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL21116504 | 0.89 | ACKR3 (0.56) | ACKR3NAMPTDPP8DPP9DPP7 | |
| SCHEMBL21116506 | 0.89 | ACKR3 (0.56) | ACKR3NAMPTDPP8DPP9DPP7 | |
| SCHEMBL30142472 | 0.89 | ACKR3 (0.56) | ACKR3NAMPTDPP8DPP9DPP7 | |
| SCHEMBL19926093 | 0.89 | ACKR3 (0.44) | ACKR3NAMPTCHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843379-B | Substituted ureas and methods of making and using the same | 梅比斯发现公司 | 2022-12-30 | — | — | CN | disclosed |