Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.82 |
| ▸ | NPC1 | O15118 | 8/20 | 0.82 |
| ▸ | RAB9A | P51151 | 8/20 | 0.82 |
| ▸ | STAT3 | P40763 | 7/20 | 0.82 |
| ▸ | MAPT | P10636 | 5/20 | 0.82 |
| ▸ | PKM | P14618 | 4/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.82 |
| ▸ | LMNA | P02545 | 3/20 | 0.82 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.82 |
| ▸ | HTT | P42858 | 2/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.82 |
| ▸ | MLNR | O43193 | 1/20 | 0.82 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.82 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.82 |
| ▸ | TP53 | P04637 | 1/20 | 0.82 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.82 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.82 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29056942 | 0.94 | STAT3 (0.83) | MEN1KMT2ANPC1RAB9ASTAT3 | |
| SCHEMBL16687504 | 0.92 | MEN1 (0.76) | MEN1KMT2ANPC1RAB9ASTAT3 | |
| Nitazoxanide SCHEMBL40981 | 0.90 | STAT3 (1.00) | MEN1KMT2ANPC1RAB9ASTAT3 | |
| Nitazoxanide SCHEMBL29373905 | 0.90 | STAT3 (1.00) | MEN1KMT2ANPC1RAB9ASTAT3 | |
| Nitazoxanide SCHEMBL5055353 | 0.90 | STAT3 (1.00) | MEN1KMT2ANPC1RAB9ASTAT3 | |
| SCHEMBL12994083 | 0.90 | NPC1 (0.79) | MEN1KMT2ANPC1RAB9ASTAT3 | |
| SCHEMBL16687500 | 0.89 | MEN1 (0.76) | MEN1KMT2ANPC1RAB9ASTAT3 | |
| SCHEMBL8463533 | 0.89 | MEN1 (0.78) | MEN1KMT2ANPC1RAB9ASTAT3 | |
| SCHEMBL16687499 | 0.89 | MEN1 (0.71) | MEN1KMT2ANPC1RAB9ASTAT3 | |
| Nitazoxanide SCHEMBL28195534 | 0.89 | STAT3 (0.98) | MEN1KMT2ANPC1RAB9ASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-02-29 | — | — | US | disclosed |
| CN-116472292-A | Modified proteins and protein degrading agents | 上海睿跃生物科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| EP-4157888-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | Cullgen (Shanghai), Inc. (CN) | 2023-04-05 | — | — | EP | disclosed |
| US-20230057177-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, MDM2 | MEN1 3254/4885KMT2A 1342/4885NPC1 3949/4885 |
| US-20230057177-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, MDM2 | MEN1 3254/4885KMT2A 1342/4885NPC1 3949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.