Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.78 |
| ▸ | NPC1 | O15118 | 9/20 | 0.78 |
| ▸ | RAB9A | P51151 | 9/20 | 0.78 |
| ▸ | MAPT | P10636 | 6/20 | 0.78 |
| ▸ | STAT3 | P40763 | 5/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | PKM | P14618 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | HTT | P42858 | 3/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | MLNR | O43193 | 1/20 | 0.78 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.78 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.78 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.78 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12994091 | 0.91 | ALDH1A1 (0.65) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL18012517 | 0.90 | ALDH1A1 (0.64) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL30142740 | 0.89 | MEN1 (0.82) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL27134627 | 0.88 | MEN1 (0.76) | MEN1KMT2ANPC1RAB9AMAPT | |
| Nitazoxanide SCHEMBL29373905 | 0.88 | STAT3 (1.00) | MEN1KMT2ANPC1RAB9AMAPT | |
| Nitazoxanide SCHEMBL5055353 | 0.88 | STAT3 (1.00) | MEN1KMT2ANPC1RAB9AMAPT | |
| Nitazoxanide SCHEMBL40981 | 0.88 | STAT3 (1.00) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL29056942 | 0.88 | STAT3 (0.83) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL19628268 | 0.88 | MEN1 (0.76) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL16687500 | 0.88 | MEN1 (0.76) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11850237-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2023-12-26 | — | — | US | disclosed |
| US-20180078533-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2018-03-22 | — | — | US | disclosed |
| US-9820975-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2017-11-21 | — | — | US | disclosed |
| US-20160228415-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2016-08-11 | — | — | US | disclosed |
| US-9345690-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2016-05-24 | — | — | US | disclosed |
| US-20150250768-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2015-09-10 | — | — | US | disclosed |
| US-9023877-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2015-05-05 | — | — | US | disclosed |
| US-5935591-A | Method for treatment of equine protozoal myeloencephalitis with thiazolides | ROMARK LABORATORIES, L.C. (US) | 1999-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150250768-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | MEN1 3237/4885KMT2A 2029/4885NPC1 473/4885 |
| US-20180078533-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | MEN1 3237/4885KMT2A 2029/4885NPC1 473/4885 |
| US-11850237-B2 | Compounds and methods for treating influenza | HIF1AN, HAVCR2, NEU1 | MEN1 3237/4885KMT2A 2029/4885NPC1 473/4885 |
| US-20160228415-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | MEN1 3237/4885KMT2A 2029/4885NPC1 473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.