Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30142983 | 0.89 | CDK2 (0.50) | SMN1; SMN2HDAC3HDAC1HDAC4HDAC7 | |
| SCHEMBL810405 | 0.86 | CYP1A2 (0.50) | SMN1; SMN2HDAC3HDAC1HDAC4HDAC7 | |
| SCHEMBL810378 | 0.82 | IKBKB (0.56) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL20095475 | 0.80 | CYP1A2 (0.53) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL7098728 | 0.80 | CYP1A2 (0.53) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL20095479 | 0.78 | IKBKB (0.50) | SMN1; SMN2HDAC1HDAC2IKBKBNAMPT | |
| SCHEMBL22147215 | 0.78 | IKBKB (0.40) | SMN1; SMN2HDAC3HDAC1HDAC4HDAC7 | |
| SCHEMBL14212498 | 0.78 | IKBKB (0.59) | SMN1; SMN2IKBKBNAMPTALDH1A1KMT2A | |
| SCHEMBL8917926 | 0.78 | IKBKB (0.59) | SMN1; SMN2IKBKBNAMPTALDH1A1KMT2A | |
| SCHEMBL30142968 | 0.76 | RAF1 (0.51) | HDAC3HDAC1HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848506-B | Biphenyl urea compound and pharmaceutical composition, preparation method and application thereof | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |