Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16736442 | 0.67 | CRBN (0.35) | — | |
| SCHEMBL28957602 | 0.64 | FGFR4 (0.51) | — | |
| SCHEMBL30978895 | 0.64 | COMT (0.37) | COMTALDH1A1GAAMAPTHTT | |
| SCHEMBL16475239 | 0.61 | COMT (0.41) | COMTALDH1A1GAAMAPTHTT | |
| SCHEMBL19538953 | 0.61 | BRD4 (0.44) | COMTALDH1A1SMN1; SMN2PRMT5WDR77 | |
| SCHEMBL2727888 | 0.59 | ALDH1A1 (0.38) | COMTALDH1A1PRMT5WDR77LRRK2 | |
| SCHEMBL4482683 | 0.59 | — | — | |
| SCHEMBL31267856 | 0.59 | BRAF (0.47) | — | |
| SCHEMBL31267997 | 0.59 | BRAF (0.70) | COMTPRMT5WDR77PDE3BPDE3A | |
| SCHEMBL24464275 | 0.59 | ALDH1A1 (0.41) | COMTALDH1A1GAAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703798-A | Azaindolinone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-02-17 | — | — | CN | disclosed |