Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.46 |
| ▸ | CECR2 | Q9BXF3 | 5/20 | 0.46 |
| ▸ | TAF1 | P21675 | 4/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 4/20 | 0.46 |
| ▸ | TAF11 | Q15544 | 1/20 | 0.46 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17758552 | 1.00 | BRD4 (0.46) | BRD4CECR2TAF1BRD9TAF11 | |
| SCHEMBL19640305 | 0.86 | CECR2 (0.51) | BRD4CECR2TAF1BRD9TAF11 | |
| SCHEMBL30143869 | 0.86 | CECR2 (0.51) | BRD4CECR2TAF1BRD9TAF11 | |
| SCHEMBL30073362 | 0.85 | CECR2 (0.46) | BRD4CECR2TAF1BRD9TAF11 | |
| SCHEMBL19657342 | 0.83 | CECR2 (0.50) | BRD4CECR2TAF1BRD9TAF11 | |
| SCHEMBL30073337 | 0.72 | CECR2 (0.51) | BRD4CECR2TAF1BRD9TAF11 | |
| SCHEMBL17749850 | 0.71 | BRD4 (0.41) | BRD4ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17755641 | 0.71 | BRD4 (0.52) | BRD4TRIM24TRIM33MAPK1 | |
| SCHEMBL19639691 | 0.70 | ALDH1A1 (0.48) | BRD4ALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL17758497 | 0.70 | CECR2 (0.57) | BRD4CECR2TAF1BRD9TAF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003409-A | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-107207493-B | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-01-20 | — | — | CN | disclosed |