Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | VEGFA | P15692 | 2/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | UBE2N | P61088 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30143871 | 0.85 | BRD4 (0.40) | BRD4HTR6VEGFAEGLN1 | |
| SCHEMBL17749850 | 0.79 | BRD4 (0.41) | BRD4HTR6VEGFAEGLN1ALDH1A1 | |
| SCHEMBL17749753 | 0.73 | BRD4 (0.37) | BRD4HTR6VEGFAEGLN1ALDH1A1 | |
| SCHEMBL17758552 | 0.70 | BRD4 (0.46) | BRD4ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30143868 | 0.70 | BRD4 (0.46) | BRD4ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19640305 | 0.69 | CECR2 (0.51) | BRD4ALDH1A1 | |
| SCHEMBL30143869 | 0.69 | CECR2 (0.51) | BRD4ALDH1A1 | |
| SCHEMBL17758546 | 0.69 | CA1 (0.42) | BRD4HTR6VEGFAEGLN1ALDH1A1 | |
| SCHEMBL23296065 | 0.68 | BRD4 (0.52) | BRD4HTR6VEGFAEGLN1CA1 | |
| SCHEMBL17756344 | 0.67 | CA1 (0.43) | BRD4HTR6VEGFAEGLN1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207493-B | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-01-20 | — | — | CN | disclosed |