Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.45 |
| ▸ | CCND1 | P24385 | 4/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | PRKACG | P22612 | 1/20 | 0.37 |
| ▸ | PRKACB | P22694 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31066760 | 1.00 | CDK4 (0.45) | CDK4CCND1NOTUMBIRC5KMT2A | |
| Hydrochloric Acid SCHEMBL7485647 | 0.98 | CDK4 (0.43) | CDK4CCND1NOTUMBIRC5KMT2A | |
| Benzene SCHEMBL29216470 | 0.98 | CDK4 (0.43) | CDK4CCND1NOTUMBIRC5KMT2A | |
| SCHEMBL6984532 | 0.84 | CDK4 (0.45) | CDK4CCND1NOTUMBIRC5KMT2A | |
| SCHEMBL2679476 | 0.81 | CDK4 (0.41) | CDK4CCND1NOTUMBIRC5KMT2A | |
| SCHEMBL22549893 | 0.77 | CDK4 (0.45) | CDK4CCND1NOTUMBIRC5KMT2A | |
| SCHEMBL645711 | 0.77 | CDK4 (0.45) | CDK4CCND1NOTUMBIRC5KMT2A | |
| SCHEMBL24218236 | 0.74 | CDK4 (0.42) | CDK4CCND1NOTUMBIRC5KMT2A | |
| SCHEMBL3177399 | 0.74 | CDK4 (0.42) | CDK4CCND1NOTUMBIRC5KMT2A | |
| SCHEMBL28979203 | 0.72 | NOTUM (0.41) | CDK4CCND1NOTUMKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865869-A | Method for synthesizing 1-trifluoromethyl indole compound by taking 2-alkynyl aromatic amine as raw material | 江南大学 | 2024-04-12 | — | — | CN | claimed |
| CN-117865870-A | Method for synthesizing 1-trifluoromethyl indole compound by taking 2-alkynyl aryl isothiocyanate as raw material | 江南大学 | 2024-04-12 | — | — | CN | claimed |
| CN-117728010-A | Solid electrolyte material, preparation method and solid battery | 蜂巢能源科技(无锡)有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117430542-B | Synthesis method of trifluoromethyl indole derivative | 上海恩氟佳科技有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117430542-A | Synthesis method of trifluoromethyl indole derivative | 上海恩氟佳科技有限公司 | 2024-01-23 | — | — | CN | claimed |
| EP-2018380-A2 | CNS ACTIVE FUSED BICYCLOHETEROCYCLE SUBSTITUTED AZABICYCLIC ALKANE DERIVATIVES | Abbott Laboratories (US) | 2009-01-28 | — | — | EP | claimed |
| WO-2007137030-A2 | CNS ACTIVE FUSED BICYCLOHETEROCYCLE SUBSTITUTED AZABICYCLIC ALKANE DERIVATIVES | ABBOTT LABORATORIES (US) | 2007-11-29 | — | — | WO | claimed |
| CN-121405607-A | N-trifluoromethyl indole compound and preparation method thereof | 中山大学 | 2026-01-27 | — | — | CN | disclosed |
| CN-121405607-A | N-trifluoromethyl indole compound and preparation method thereof | 中山大学 | 2026-01-27 | — | — | CN | disclosed |
| CN-120158215-A | Multifunctional water paint for engine and preparation method thereof | 陕西虹瑞化工科技有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-117865870-A | Method for synthesizing 1-trifluoromethyl indole compound by taking 2-alkynyl aryl isothiocyanate as raw material | 江南大学 | 2024-04-12 | — | — | CN | disclosed |
| CN-117865870-A | Method for synthesizing 1-trifluoromethyl indole compound by taking 2-alkynyl aryl isothiocyanate as raw material | 江南大学 | 2024-04-12 | — | — | CN | disclosed |
| CN-117865870-A | Method for synthesizing 1-trifluoromethyl indole compound by taking 2-alkynyl aryl isothiocyanate as raw material | 江南大学 | 2024-04-12 | — | — | CN | disclosed |
| US-5641800-A | ALLEVIATE EFFECT OF SEPTIC SHOCK, ADULT RESPIRATORY DISTRESS SYNDROME, PANCREATITIS, TRAUMA, BRONCHIAL ASTHMA, ALLERGIC RHINITIS, AND RHEUMATOID ARTHRITIS | ELI LILLY AND COMPANY (US) | 1997-06-24 | — | — | US | disclosed |
| EP-0769940-A4 | — | — | 1997-06-11 | — | — | EP | disclosed |
| EP-0772596-A1 | INDOLIZINE sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1997-05-14 | — | — | EP | disclosed |
| EP-0769940-A1 | INDENE sPLA 2? INHIBITORS | ELI LILLY AND COMPANY (US) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996003120-A1 | INDENE sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-02-08 | — | — | WO | disclosed |
| WO-1996003383-A1 | INDOLIZINE sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-02-08 | — | — | WO | disclosed |
| EP-0675110-A1 | 1H-Indole-3-glyoxylamide sPLA2 inhibitors | ELI LILLY AND COMPANY (US) | 1995-10-04 | — | — | EP | disclosed |