Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.45 |
| ▸ | CCND1 | P24385 | 4/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | PRKACG | P22612 | 1/20 | 0.36 |
| ▸ | PRKACB | P22694 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31066760 | 0.84 | CDK4 (0.45) | CDK4CCND1NOTUMBIRC5KMT2A | |
| SCHEMBL30144 | 0.84 | CDK4 (0.45) | CDK4CCND1NOTUMBIRC5KMT2A | |
| Hydrochloric Acid SCHEMBL7485647 | 0.83 | CDK4 (0.43) | CDK4CCND1NOTUMBIRC5KMT2A | |
| Benzene SCHEMBL29216470 | 0.83 | CDK4 (0.43) | CDK4CCND1NOTUMBIRC5KMT2A | |
| SCHEMBL2679476 | 0.79 | CDK4 (0.41) | CDK4CCND1NOTUMBIRC5KMT2A | |
| SCHEMBL22549893 | 0.76 | CDK4 (0.45) | CDK4CCND1NOTUMBIRC5KMT2A | |
| SCHEMBL645711 | 0.76 | CDK4 (0.45) | CDK4CCND1NOTUMBIRC5KMT2A | |
| SCHEMBL24218236 | 0.72 | CDK4 (0.42) | CDK4CCND1NOTUMBIRC5KMT2A | |
| SCHEMBL3177399 | 0.72 | CDK4 (0.42) | CDK4CCND1NOTUMBIRC5KMT2A | |
| SCHEMBL18379331 | 0.71 | CDK4 (0.54) | CDK4CCND1NOTUMBIRC5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924209-B1 | Hypoglycemic imidazoline compounds | LILLY CO ELI (US) | 2003-05-02 | — | — | EP | claimed |