Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.59 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | BCR | P11274 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226295 | 1.00 | ALDH1A1 (0.65) | ALDH1A1CYP19A1CYP11B1CYP11B2SLC2A1 | |
| SCHEMBL30748659 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CYP19A1CYP11B1CYP11B2CYP2A6 | |
| SCHEMBL2316603 | 0.83 | TSHR (0.59) | ALDH1A1NEK1SMN1; SMN2GABRA5KDM4E | |
| SCHEMBL2345607 | 0.82 | CYP19A1 (0.74) | ALDH1A1CYP19A1CYP11B1CYP11B2SLC2A1 | |
| SCHEMBL4636333 | 0.81 | HPGDS (0.57) | ALDH1A1NEK1KDM4EMAPK1HPGD | |
| SCHEMBL3511516 | 0.81 | CYP19A1 (0.68) | ALDH1A1CYP19A1CYP11B1CYP11B2SLC2A1 | |
| SCHEMBL10028698 | 0.81 | CYP19A1 (0.68) | ALDH1A1CYP19A1CYP11B1CYP11B2SLC2A1 | |
| SCHEMBL30151105 | 0.80 | ABL1 (0.66) | ALDH1A1CYP19A1CYP11B1CYP11B2SLC2A1 | |
| SCHEMBL3713394 | 0.80 | ABL1 (0.66) | ALDH1A1CYP19A1CYP11B1CYP11B2SLC2A1 | |
| SCHEMBL21994688 | 0.80 | PDGFRB (0.61) | ALDH1A1CYP19A1CYP11B1CYP11B2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997674-B | 6-5 fused rings as C5a inhibitors | 凯莫森特里克斯股份有限公司 | 2022-12-20 | — | — | CN | disclosed |