SCHEMBL3014429

SCHEMBL3014429

O=C=Nc1ccc2oc3ccccc3c2c1N=C=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.40
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CYP3A4 P08684 2/20 0.40
GLA P06280 2/20 0.40
PGAM1 P18669 1/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21624973 0.81 CYP3A4 (0.46) MAOAALDH1A1KDM4EMAPTHPGD
SCHEMBL21763556 0.76 MAOA (0.47) MAOAALDH1A1KDM4EMAPTHPGD
SCHEMBL20267804 0.73 KDM4E (0.41) MAOAALDH1A1KDM4EMAPTHPGD
SCHEMBL29500990 0.70 TDP1 (0.41) MAOAALDH1A1KDM4EMAPTHPGD
SCHEMBL38584 0.70 TDP1 (0.41) MAOAALDH1A1KDM4EMAPTHPGD
SCHEMBL29405309 0.70 CYP3A4 (0.50) MAOAALDH1A1MAPTHPGDCYP3A4
SCHEMBL27066 0.70 CYP3A4 (0.50) MAOAALDH1A1MAPTHPGDCYP3A4
SCHEMBL5577120 0.70 CYP3A4 (0.48) ALDH1A1HPGDCYP3A4TDP1GABRA1
SCHEMBL1635475 0.70 MAOA (0.59) MAOAALDH1A1KDM4EMAPTHPGD
SCHEMBL4126697 0.68 MAOA (0.48) MAOAALDH1A1KDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371628-A Acetal structure-containing acid enzyme-controllable degradable polyurethane and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2025-01-28 CN claimed
CN-119371628-A Acetal structure-containing acid enzyme-controllable degradable polyurethane and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2025-01-28 CN disclosed
EP-3643735-B1 PHOTOCHROMIC POLYROTAXANE COMPOUND, AND CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC POLYROTAXANE COMPOUND TOKUYAMA CORP (JP) 2024-07-31 EP disclosed
US-20240101751-A1 HOLLOW MICROBALLOON TOKUYAMA CORPORATION (JP) 2024-03-28 US disclosed
US-20240084067-A1 NOVEL CURABLE COMPOSITION CONTAINING CYCLIC MONOMER TOKUYAMA CORPORATION (JP) 2024-03-14 US disclosed
US-11912813-B2 Urethane resin using polyrotaxane, and pad for polishing TOKUYAMA CORPORATION (JP) 2024-02-27 US disclosed
US-20230390890-A1 POLYMERIZABLE FUNCTIONAL GROUP-CONTAINING MICROBALLOON TOKUYAMA CORPORATION (JP) 2023-12-07 US disclosed
EP-4286439-A1 HOLLOW MICROBALLOON Tokuyama Corporation (JP) 2023-12-06 EP disclosed
EP-4286435-A1 NOVEL CURABLE COMPOSITION CONTAINING CYCLIC MONOMER Tokuyama Corporation (JP) 2023-12-06 EP disclosed
US-20230365739-A1 CURABLE COMPOSITION AND CURED ARTICLE THEREOF TOKUYAMA CORPORATION (JP) 2023-11-16 US disclosed
US-5194559-A Reacting compounds containing isocyanate and isothiocyanate groups with polyol and polythiol; colorlrss, transparent MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-16 US disclosed
US-5191055-A Polythiourethanes MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-02 US disclosed
EP-0528590-A1 Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-02-24 EP disclosed
EP-0506315-A2 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-30 EP disclosed
EP-0505150-A1 Stabilizing method of isocyanate compounds and isocyanate compositions stabilized thereby MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-23 EP disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
US-4946923-A S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-08-07 US disclosed
EP-0378895-A1 A mercapto compound, a high refractive index resin and lens and a process for preparing them MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-25 EP disclosed
EP-0329388-A2 Plastic lenses having high-refractive index and process for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
EP-0329386-A2 S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed