Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18299704 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAATTRALB | |
| SCHEMBL98131 | 0.84 | TTR (0.48) | ALDH1A1KDM4EGAATTRALB | |
| Iodide SCHEMBL1704562 | 0.82 | TTR (0.46) | ALDH1A1KDM4EGAATTRALB | |
| SCHEMBL11277214 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAALOXL2EGLN2 | |
| SCHEMBL29443092 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAALOXL2EGLN2 | |
| SCHEMBL352155 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAALOXL2EGLN2 | |
| SCHEMBL21687453 | 0.78 | TTR (0.52) | ALDH1A1TTRALBLOXL2CYP2A6 | |
| Ammonia Solution, Strong SCHEMBL5952367 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAALOXL2EGLN2 | |
| SCHEMBL2419320 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAALOXL2EGLN2 | |
| SCHEMBL3840579 | 0.74 | TTR (0.43) | ALDH1A1TTRALBLOXL2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022254218-A1 | PROCESSES FOR THE PREPARATION OF INHIBITORY COMPOUNDS | STORM THERAPEUTICS LTD (GB) | 2022-12-08 | — | — | WO | disclosed |