SCHEMBL352155

SCHEMBL352155

N#Cc1ccc(N)c(N)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
TDP1 Q9NUW8 3/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
LOXL2 Q9Y4K0 1/20 0.41
CYP3A4 P08684 2/20 0.40
ALOX15 P16050 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CYP2A6 P11509 2/20 0.40
TSHR P16473 2/20 0.40
TP53 P04637 1/20 0.40
THRB P10828 1/20 0.40
CA12 O43570 1/20 0.40
CA2 P00918 1/20 0.40
CA3 P07451 1/20 0.40
CA6 P23280 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29443092 1.00 ALDH1A1 (0.50) ALDH1A1KDM4EGAATDP1MEN1
SCHEMBL11277214 1.00 ALDH1A1 (0.50) ALDH1A1KDM4EGAATDP1MEN1
Ammonia Solution, Strong SCHEMBL5952367 0.97 ALDH1A1 (0.48) ALDH1A1KDM4EGAATDP1MEN1
SCHEMBL21277388 0.82 ALDH1A1 (0.44) ALDH1A1KDM4EGAALOXL2CYP2A6
SCHEMBL15156687 0.81 TDP1 (0.61) ALDH1A1TDP1MEN1KMT2ALOXL2
SCHEMBL29655663 0.81 TDP1 (0.61) ALDH1A1TDP1MEN1KMT2ALOXL2
SCHEMBL30702253 0.80 ALDH1A1 (0.43) ALDH1A1KDM4EGAAMEN1KMT2A
SCHEMBL3440802 0.80 ALDH1A1 (0.43) ALDH1A1KDM4EGAAMEN1KMT2A
SCHEMBL98131 0.80 TTR (0.48) ALDH1A1KDM4EGAALOXL2CYP2A6
SCHEMBL2419320 0.80 ALDH1A1 (0.47) ALDH1A1KDM4EGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 980 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271295-A Dibenzophenazine derivative luminescent material and preparation method and application thereof 大连理工大学 2024-07-02 CN claimed
CN-117946084-A Linear aza D-A type nonlinear optical material, and preparation method and application thereof 浙江工业大学 2024-04-30 CN claimed
CN-114805805-B Polyimide with high adhesive strength and preparation method and application thereof 深圳先进电子材料国际创新研究院 2023-12-19 CN claimed
CN-114920929-B Lithium ion battery anode material, lithium ion battery anode, lithium ion battery and preparation method and application thereof 北京化工大学 2023-10-20 CN claimed
CN-116715860-A Hydrogen bond organic framework material and preparation method and application thereof 东北师范大学 2023-09-08 CN claimed
CN-116315315-A Organic negative electrode and metal-air battery 中国科学院深圳理工大学(筹) 2023-06-23 CN claimed
CN-116063238-A Java oxine compound and preparation method thereof 上海交通大学 2023-05-05 CN claimed
CN-114920929-A Lithium ion battery anode material, lithium ion battery anode, lithium ion battery and preparation method and application thereof 北京化工大学 2022-08-19 CN claimed
CN-114805805-A Polyimide with high bonding strength and preparation method and application thereof 中国科学院深圳先进技术研究院 2022-07-29 CN claimed
CN-111808097-B Solvent yellow 184 derivative and preparation method and application thereof 厦门大学 2021-10-22 CN claimed
WO-2015019270-A1 CYANATED NAPHTHALENEBENZIMIDAZOLE COMPOUNDS BASF SE (DE) 2015-02-12 WO claimed
WO-2011121597-A1 A PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED 3-(5-NITRO-4-THIOCYANATOPYRIMIDIN-2-YL)-3H-BENZO [d]-IMIDAZOLE NEULAND LABORATORIES LTD. (IN) 2011-10-06 WO claimed
US-7517893-B2 Bichalcophenes and their prodrugs as antiprotozoal agents THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2009-04-14 US claimed
EP-1726589-B1 5,5'-bis-(4-amidinophenyl)-2,2'-bifuran derivatives and related compounds as antiprotozoal agent and prodrugs thereof UNIV NORTH CAROLINA (US) 2008-10-15 EP claimed
CN-1935797-A Bichalcophenes and prodrugs thereof as antiprotozoal agents UNIV NORTH CAROLINA (US) 2007-03-28 CN claimed
US-20060293540-A1 Novel bichalcophenes and their prodrugs as antiprotozoal agents TIDWELL RICHARD R 2006-12-28 US claimed
EP-1726589-A2 5,5'-bis-(4-amidinophenyl)-2,2'-bifuran derivatives and related compounds as antiprotozoal agent and prodrugs thereof UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2006-11-29 EP claimed
EP-1590332-A1 A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND ITS DERIVATIONS University of Delhi (IN) 2005-11-02 EP claimed
WO-2004063170-A1 A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND ITS DERIVATIONS UNIVERSITY OF DELHI (IN) 2004-07-29 WO claimed
US-4061856-A TO 1,3,5-TRIAZINES, SULFONIC, SULFINIC, PHOSPHONIC OR PHOSPHINIC ACID OR METAL ACETYLACETONATE CATALYST THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1977-12-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060293540-A1 Novel bichalcophenes and their prodrugs as antiprotozoal agents CASP7, DDT, BAD ALDH1A1 2430/4885KDM4E 1472/4885GAA 1844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.