Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30063522 | 1.00 | KDM4E (0.56) | KDM4EAOC3AHRNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7485650 | 1.00 | KDM4E (0.56) | KDM4EAOC3AHRNPC1RAB9A | |
| Methyl Alcohol SCHEMBL28456866 | 0.94 | KDM4E (0.51) | KDM4EAOC3AHRNPC1RAB9A | |
| Benzenethiol SCHEMBL28338725 | 0.89 | KDM4E (0.47) | KDM4EAOC3AHRNPC1RAB9A | |
| Benzyl Alcohol SCHEMBL28459276 | 0.85 | IDO1 (0.44) | KDM4EAOC3AHRNPC1RAB9A | |
| SCHEMBL27459103 | 0.83 | KDM4E (0.46) | KDM4EAOC3AHRNPC1RAB9A | |
| SCHEMBL28864005 | 0.82 | AHR (0.53) | KDM4EAOC3AHRNPC1RAB9A | |
| SCHEMBL4419425 | 0.80 | AHR (0.53) | KDM4EAOC3AHRNPC1RAB9A | |
| SCHEMBL7022968 | 0.80 | AHR (0.51) | KDM4EAOC3AHRNPC1RAB9A | |
| SCHEMBL14694209 | 0.80 | AOC3 (0.56) | KDM4EAOC3AHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117728010-A | Solid electrolyte material, preparation method and solid battery | 蜂巢能源科技(无锡)有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117430542-B | Synthesis method of trifluoromethyl indole derivative | 上海恩氟佳科技有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117430542-A | Synthesis method of trifluoromethyl indole derivative | 上海恩氟佳科技有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-113563334-B | 3-fluoro-beta-carboline compound and preparation method and application thereof | 南京林业大学 | 2022-05-03 | — | — | CN | claimed |
| CN-113185445-A | Green synthesis method of 2-trifluoromethyl indole | 国药集团化学试剂有限公司 | 2021-07-30 | — | — | CN | claimed |
| CN-107619385-B | Method for synthesizing 2-trifluoromethyl indole by palladium-catalyzed aryl enamine intramolecular amine | 温州大学 | 2020-02-21 | — | — | CN | claimed |
| US-12612389-B2 | Benzofuran-based N-acylhydrazone derivative and pharmaceutical composition comprising same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2026-04-28 | — | — | US | disclosed |
| CN-121652049-A | Indole derivative difluoromethylation and [18F ] radiolabelling method thereof | 遵义医科大学 | 2026-03-13 | — | — | CN | disclosed |
| CN-120158215-A | Multifunctional water paint for engine and preparation method thereof | 陕西虹瑞化工科技有限公司 | 2025-06-17 | — | — | CN | disclosed |
| US-20250171420-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | MONTE ROSA THERAPEUTICS AG (CH) | 2025-05-29 | — | — | US | disclosed |
| CN-117088803-B | 1-Trifluoromethyl cyclopentadiene [ b ] indole compound and preparation method and application thereof | 南京林业大学 | 2024-11-05 | — | — | CN | disclosed |
| CN-114206857-B | Benzofuranyl N-acylhydrazone derivatives and pharmaceutical compositions comprising the same | 韩国生命工学研究院 | 2024-09-06 | — | — | CN | disclosed |
| CN-118406001-A | Preparation method and application of trifluoromethyl substituted indole compound promoted by visible light | 华东理工大学 | 2024-07-30 | — | — | CN | disclosed |
| WO-1996003120-A1 | INDENE sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-02-08 | — | — | WO | disclosed |
| EP-0675110-A1 | 1H-Indole-3-glyoxylamide sPLA2 inhibitors | ELI LILLY AND COMPANY (US) | 1995-10-04 | — | — | EP | disclosed |
| US-5204471-A | α-trifluoromethyl-substituted, saturated bicyclic amines | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-20 | — | — | US | disclosed |
| EP-0527385-A1 | Alpha-trifluoromethyl substituted, saturated bicyclic amines and process for their preparation | BAYER AG (DE) | 1993-02-17 | — | — | EP | disclosed |
| EP-0261035-B1 | INDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE IN COMBATING PARASITES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1992-03-11 | — | — | EP | disclosed |
| US-4849443-A | Indoles and pesticidal use thereof | ROUSSEL UCLAF (FR) | 1989-07-18 | — | — | US | disclosed |
| EP-0261035-A1 | Indole derivatives, process for their preparation, their use in combating parasites and compositions containing them | ROUSSEL-UCLAF (FR) | 1988-03-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171420-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | PSMA1, CSNK1G1, CSNK1A1 | KDM4E 394/4885AOC3 3519/4885AHR 4306/4885 |
| US-12612389-B2 | Benzofuran-based N-acylhydrazone derivative and pharmaceutical composition comprising same | TUBB3, TUBA1C, ACIN1 | KDM4E 2935/4885AOC3 2184/4885AHR 811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.