Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 17/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 17/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20294344 | 1.00 | PDCD1 (0.43) | PDCD1CD274HTR2CNPC1RAB9A | |
| SCHEMBL31711064 | 0.87 | HTR2C (0.45) | PDCD1CD274HTR2CNPC1RAB9A | |
| SCHEMBL20294458 | 0.86 | PDCD1 (0.43) | PDCD1CD274NPC1RAB9A | |
| SCHEMBL20294409 | 0.86 | PDCD1 (0.51) | PDCD1CD274HTR2CNPC1RAB9A | |
| SCHEMBL20294060 | 0.85 | PDCD1 (0.49) | PDCD1CD274HTR2C | |
| SCHEMBL30145292 | 0.82 | HTR2C (0.41) | PDCD1CD274HTR2CSPR | |
| SCHEMBL20293398 | 0.82 | HTR2C (0.41) | PDCD1CD274HTR2CSPR | |
| SCHEMBL19549674 | 0.75 | GRAMD1A (0.47) | PDCD1CD274NPC1RAB9ASPR | |
| SCHEMBL30740239 | 0.75 | GRAMD1A (0.47) | PDCD1CD274NPC1RAB9ASPR | |
| SCHEMBL20331241 | 0.72 | PDCD1 (0.50) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110267953-B | Tetrahydroimidazo [4,5-C ] pyridine derivatives as inducers of PD-L1 internalization | 因赛特公司 | 2022-12-20 | — | — | CN | disclosed |