Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 4/20 | 0.43 |
| ▸ | BRD2 | P25440 | 2/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.43 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24815213 | 0.80 | ALOX15 (0.41) | HPGDSMN1; SMN2ALOX15CHRNA7BAZ2B | |
| SCHEMBL28926127 | 0.79 | TSHR (0.46) | TSHRHTTSMN1; SMN2CA2 | |
| SCHEMBL31183046 | 0.79 | ALOX15 (0.34) | HPGDSMN1; SMN2ALOX15CHRNA7 | |
| SCHEMBL25510415 | 0.78 | HTR1B (0.40) | ALOX15CHRNA7 | |
| SCHEMBL38661799 | 0.77 | ALOX15 (0.41) | TSHRCA2ALOX15CHRNA7 | |
| SCHEMBL25139824 | 0.76 | MAPT (0.44) | HPGDTSHRHTTSMN1; SMN2ALOX15 | |
| SCHEMBL30147670 | 0.76 | HDAC8 (0.47) | HDAC8HDAC6HDAC2HPGDTSHR | |
| SCHEMBL25139593 | 0.76 | KDM4E (0.41) | TSHRALOX15CHRNA7 | |
| SCHEMBL13795590 | 0.75 | MMP13 (0.44) | HDAC8HDAC6HDAC2BRD4BRD2 | |
| SCHEMBL25515106 | 0.74 | CHRNA7 (0.33) | ALOX15CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |