Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | CXCR5 | P32302 | 8/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10999638 | 1.00 | HDAC9 (0.46) | HDAC9CXCR5HTR2AHTR2CHRH1 | |
| SCHEMBL11411488 | 0.86 | CXCR5 (0.40) | HDAC9CXCR5HTR2AHTR2CHRH1 | |
| SCHEMBL30863938 | 0.78 | MMP8 (0.47) | HDAC9CXCR5THRBTDP1MME | |
| SCHEMBL1014144 | 0.78 | MMP8 (0.47) | HDAC9CXCR5THRBTDP1MME | |
| SCHEMBL9439533 | 0.74 | HDAC9 (0.44) | HDAC9CXCR5HTR2AHTR2CHRH1 | |
| SCHEMBL27558944 | 0.74 | HDAC9 (0.44) | HDAC9CXCR5HTR2AHTR2CHRH1 | |
| SCHEMBL122942 | 0.74 | HDAC9 (0.44) | HDAC9CXCR5MMEAKR1C1MMP8 | |
| SCHEMBL1786936 | 0.74 | HDAC9 (0.44) | HDAC9CXCR5HTR2AHTR2CHRH1 | |
| SCHEMBL29476532 | 0.74 | HDAC9 (0.44) | HDAC9CXCR5MMEAKR1C1MMP8 | |
| SCHEMBL30147622 | 0.74 | HDAC9 (0.44) | HDAC9CXCR5MMEMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195053-B | Amino acid compounds and methods of use | 普利安特治疗公司 | 2024-08-30 | — | — | CN | disclosed |
| EP-4405352-A1 | NEW COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | F. Hoffmann-La Roche AG (CH) | 2024-07-31 | — | — | EP | disclosed |
| WO-2023041756-A1 | NEW COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2023-03-23 | — | — | WO | disclosed |
| EP-4149945-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2023-03-22 | — | — | EP | disclosed |
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |