SCHEMBL1014144

SCHEMBL1014144

O=C(O)C1(C(=O)O)Cc2ccccc2C1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 3/20 0.47
HDAC9 Q9UKV0 1/20 0.47
CXCR5 P32302 3/20 0.41
MME P08473 1/20 0.41
CYP2D6 P10635 1/20 0.40
AKR1C1 Q04828 1/20 0.40
POLB P06746 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
THRB P10828 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
NOTUM Q6P988 1/20 0.37
DAO P14920 1/20 0.36
TSHR P16473 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
ALDH1A1 P00352 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30863938 1.00 MMP8 (0.47) MMP8HDAC9CXCR5MMECYP2D6
SCHEMBL30684801 0.85 MMP8 (0.41) MMP8HDAC9CXCR5CYP2D6AKR1C1
SCHEMBL7445797 0.82 MEN1 (0.45) MMP8HDAC9CXCR5MMEPOLB
SCHEMBL10427685 0.80 MAPT (0.35) MMP8HDAC9CYP2D6AKR1C1POLB
SCHEMBL10999638 0.78 HDAC9 (0.46) MMP8HDAC9CXCR5MMEAKR1C1
SCHEMBL8078233 0.78 NOTUM (0.45) MMP8HDAC9POLBL3MBTL1TDP1
SCHEMBL30645248 0.78 NOTUM (0.45) MMP8HDAC9POLBL3MBTL1TDP1
SCHEMBL30147508 0.78 HDAC9 (0.46) MMP8HDAC9CXCR5MMEAKR1C1
SCHEMBL3309675 0.78 BRD4 (0.50) POLBTSHRALDH1A1
SCHEMBL27006578 0.78 POLB (0.38) MMP8HDAC9POLBL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102443316-B curable phase change inks containing crystalline polyester Xerox Corp. (US) Patent Dept. 020 Xerox Square 100 Clinton Avenue Rochester New (US) 2016-02-03 CN claimed
US-8657430-B2 Curable phase change inks containing crystalline polyesters XEROX CORPORATION (US) 2014-02-25 US claimed
US-8613506-B2 2013-12-24 US claimed
CN-102443316-A Curable phase change inks containing crystalline polyesters XEROX CORP 2012-05-09 CN claimed
US-20120086761-A1 CURABLE PHASE CHANGE INKS CONTAINING CRYSTALLINE POLYESTERS XEROX CORPORATION (US) 2012-04-12 US claimed
WO-2025079647-A1 TRANSPARENTIZING AGENT, METHOD FOR PRODUCING SAME, TRANSPARENT PAPER, AND METHOD FOR PRODUCING SAME 王子ホールディングス株式会社 2025-04-17 WO disclosed
US-12077611-B2 Cyclic peptides multimers targeting α4β7 integrin ZEALAND PHARMA A/S (DK) 2024-09-03 US disclosed
US-20240228824-A1 AQUEOUS COATING AGENT, ARTICLE, AND METHOD OF PRODUCING ROSIN-MODIFIED POLYESTER RESIN HARIMA CHEMICALS, INCORPORATED (JP) 2024-07-11 US disclosed
EP-4342956-A1 AQUEOUS COATING AGENT, ARTICLE, AND PRODUCTION METHOD OF ROSIN-MODIFIED POLYESTER RESIN Harima Chemicals, Incorporated (JP) 2024-03-27 EP disclosed
CN-117677681-A Aqueous coating agent, article, and method for producing rosin-modified polyester resin 哈利玛化成株式会社 2024-03-08 CN disclosed
US-20230406884-A1 CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN ZEALAND PHARMA A/S (DK) 2023-12-21 US disclosed
US-11713338-B2 Cyclic peptides multimers targeting α-4-β-7 integrin ZEALAND PHARMA A/S (DK) 2023-08-01 US disclosed
WO-1994019349-A1 XANTHINE DERIVATIVES AS ADENOSINE A1 RECEPTOR ANTAGONISTS MERRELL DOW PHARMACEUTICALS INC. (US) 1994-09-01 WO disclosed
EP-0449175-A2 Selective adenosine receptor agents MERRELL PHARMACEUTICALS INC. (US) 1991-10-02 EP disclosed
US-5047534-A Xanthine derivatives; hyupotensive agents, cardiotonic agents MERRELL DOW PHARMACEUTICALS INC. (US) 1991-09-10 US disclosed
WO-1991009840-A1 MERCAPTOCYCLOACYL AMINOACID ENDOPEPTIDASE INHIBITORS SCHERING CORPORATION (US) 1991-07-11 WO disclosed
EP-0135177-B1 BENZOCYCLOALKANE DERIVATIVES DAIICHI SEIYAKU CO., LTD. (JP) 1989-12-06 EP disclosed
US-4777257-A CARDIOVASCULAR DISORDERS DAIICHI SEIYAKU CO., LTD. (JP) 1988-10-11 US disclosed
US-4665188-A Certain [(1-imidazolyl)-lower-alkylene]-tetrahydronaphthalenecarboxylic acids or corresponding idan-carboxylic acids which are thromboxane A2 DAIICHI SEIYAKU CO., LTD. (JP) 1987-05-12 US disclosed
EP-0135177-A2 Benzocycloalkane derivatives DAIICHI SEIYAKU CO., LTD. (JP) 1985-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12077611-B2 Cyclic peptides multimers targeting α4β7 integrin ITGB7, ITGB4, ITGA4 MMP8 605/4885HDAC9 1221/4885CXCR5 89/4885
US-20230406884-A1 CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN ITGB7, ITGB4, ITGA4 MMP8 664/4885HDAC9 1590/4885CXCR5 151/4885
US-11713338-B2 Cyclic peptides multimers targeting α-4-β-7 integrin ITGB7, ITGB4, ITGA4 MMP8 740/4885HDAC9 1455/4885CXCR5 143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.