Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 5/20 | 0.37 |
| ▸ | IL2 | P60568 | 5/20 | 0.37 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22717957 | 0.83 | MEN1 (0.44) | HRH4EIF4A3KMT2AKDM4EALDH1A1 | |
| SCHEMBL30147671 | 0.82 | ALOX15 (0.50) | ALOX15TLR8TLR7NUDT1HRH4 | |
| SCHEMBL22718098 | 0.82 | EIF4A3 (0.50) | EIF4A3KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL29504847 | 0.82 | EIF4A3 (0.50) | EIF4A3KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL30147706 | 0.77 | HRH4 (0.56) | ALOX15HRH4ALBIL2 | |
| SCHEMBL30147479 | 0.76 | ALOX15 (0.43) | ALOX15NUDT1ALBIL2NPC1 | |
| SCHEMBL30471285 | 0.74 | IDO1 (0.54) | ALOX15NUDT1HRH4KMT2A | |
| SCHEMBL30147485 | 0.73 | ALOX15 (0.40) | ALOX15TLR8TLR7NUDT1EIF4A3 | |
| SCHEMBL24038450 | 0.72 | KEAP1 (0.45) | ALOX15KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL18183345 | 0.72 | CNR1 (0.48) | ALOX15NUDT1HRH4EIF4A3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |