Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | ULK1 | O75385 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30147671 | 0.83 | ALOX15 (0.50) | ALOX15KMT2AMEN1NUDT1NPC1 | |
| SCHEMBL19332395 | 0.82 | ULK1 (0.50) | EIF4A3KMT2AMEN1KDM4EGAA | |
| SCHEMBL18183345 | 0.81 | CNR1 (0.48) | ALOX15EIF4A3KMT2AMEN1NUDT1 | |
| SCHEMBL29946251 | 0.80 | EIF4A3 (0.57) | EIF4A3KMT2AMEN1KDM4EGAA | |
| SCHEMBL22395159 | 0.80 | EIF4A3 (0.57) | EIF4A3KMT2AMEN1KDM4EGAA | |
| SCHEMBL30544767 | 0.77 | PTPN11 (0.41) | ALOX15EIF4A3KMT2ANUDT1CREBBP | |
| SCHEMBL29824257 | 0.77 | ALOX15 (0.58) | ALOX15EIF4A3KMT2AMEN1NPC1 | |
| SCHEMBL30147706 | 0.76 | HRH4 (0.56) | ALOX15HRH4GAA | |
| SCHEMBL30147453 | 0.76 | NPC1 (0.48) | ALOX15EIF4A3KMT2AMEN1NUDT1 | |
| SCHEMBL22620680 | 0.75 | KDM4E (0.51) | ALOX15KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |