SCHEMBL30148003

SCHEMBL30148003

NC(=O)Cc1ccc(F)cc1F

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 1/20 0.52
IDO1 P14902 2/20 0.50
AGXT P21549 2/20 0.50
CES2 O00748 2/20 0.45
CES1 P23141 2/20 0.45
ICMT O60725 3/20 0.44
MAOB P27338 1/20 0.44
RIPK1 Q13546 2/20 0.43
MPO P05164 1/20 0.43
SLC6A4 P31645 1/20 0.43
P2RX7 Q99572 1/20 0.43
SIGMAR1 Q99720 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1115269 1.00 MAPK8 (0.52) MAPK8IDO1AGXTCES2CES1
Hydrochloric Acid SCHEMBL8894497 0.98 IDO1 (0.52) MAPK8IDO1AGXTCES2CES1
SCHEMBL16257133 0.84 IDO1 (0.46) MAPK8IDO1AGXTCES2CES1
SCHEMBL28037697 0.84 CA3 (0.45) MAPK8ICMTMPOSLC6A4KDM4E
SCHEMBL31078296 0.84 IDO1 (0.46) MAPK8IDO1AGXTCES2CES1
SCHEMBL1115079 0.84 MAPK8 (0.52) MAPK8CES2CES1ICMTRIPK1
SCHEMBL835045 0.84 IDO1 (0.46) MAPK8IDO1AGXTCES2CES1
SCHEMBL1288294 0.83 IDO1 (0.48) MAPK8IDO1AGXTCES2CES1
SCHEMBL29837313 0.82 CHRNA7 (0.49) MAPK8ICMT
SCHEMBL503325 0.82 TSHR (0.53) MAPK8IDO1AGXTCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115707739-A Water-resistant fiberboard and preparation method thereof 河北鑫鑫木业有限公司 2023-02-21 CN claimed
CN-115707739-B Waterproof fiber board and preparation method thereof 河北鑫鑫木业有限公司 2024-02-23 CN disclosed
CN-115707739-A Water-resistant fiberboard and preparation method thereof 河北鑫鑫木业有限公司 2023-02-21 CN disclosed