Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | ICMT | O60725 | 3/20 | 0.44 |
| ▸ | MPO | P05164 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115269 | 0.84 | MAPK8 (0.52) | ICMTMPOSLC6A4MAPK8KDM4E | |
| SCHEMBL30148003 | 0.84 | MAPK8 (0.52) | ICMTMPOSLC6A4MAPK8KDM4E | |
| SCHEMBL2395772 | 0.83 | TSHR (0.54) | CA3CA6CA5ACA9CA14 | |
| Hydrochloric Acid SCHEMBL8894497 | 0.82 | IDO1 (0.52) | ICMTMPOSLC6A4MAPK8KDM4E | |
| SCHEMBL28875498 | 0.82 | MEN1 (0.58) | MEN1KMT2ACA2 | |
| SCHEMBL1395757 | 0.81 | ALDH1A1 (0.44) | ICMTMPOSLC6A4MEN1KMT2A | |
| SCHEMBL1345638 | 0.81 | P2RX7 (0.45) | ICMTMPOSLC6A4MAPK8 | |
| SCHEMBL14495394 | 0.81 | P2RX7 (0.47) | ICMTMPOSLC6A4HTT | |
| SCHEMBL29718887 | 0.81 | ALDH1A1 (0.44) | ICMTMPOSLC6A4MEN1KMT2A | |
| SCHEMBL1115079 | 0.80 | MAPK8 (0.52) | CA3CA6CA5ACA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164124-B | Compounds and compositions for treating parasitic diseases | 诺华股份有限公司 | 2017-03-15 | — | — | CN | disclosed |
| CN-105164124-A | Compounds and compositions for treating parasitic diseases | NOVARTIS AG | 2015-12-16 | — | — | CN | disclosed |