Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 14/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29525364 | 1.00 | NTRK1 (0.50) | NTRK1RIPK1APPHTR1AADRA2A | |
| SCHEMBL932474 | 1.00 | NTRK1 (0.50) | NTRK1RIPK1APPHTR1AADRA2A | |
| SCHEMBL932475 | 1.00 | NTRK1 (0.50) | NTRK1RIPK1APPHTR1AADRA2A | |
| SCHEMBL17041234 | 0.90 | RIPK1 (0.50) | NTRK1RIPK1APPHTR1AADRA2A | |
| SCHEMBL21319501 | 0.90 | NPSR1 (0.52) | NTRK1RIPK1APPHTR1AADRA2A | |
| SCHEMBL2598872 | 0.89 | RIPK1 (0.46) | NTRK1RIPK1APPHTR1AADRA2A | |
| SCHEMBL15154729 | 0.89 | RIPK1 (0.46) | NTRK1RIPK1APPHTR1AADRA2A | |
| SCHEMBL28660312 | 0.87 | HSP90AA1 (0.47) | NTRK1RIPK1APPHTR1AADRA2A | |
| SCHEMBL38652201 | 0.86 | RIPK1 (0.42) | NTRK1RIPK1APPHTR1AADRA2A | |
| SCHEMBL29747367 | 0.85 | UCHL1 (0.48) | RIPK1APPHTR1AADRA2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710210-A | Iron catalyzed amination of C-H bonds | 港大科桥有限公司 | 2023-02-24 | — | — | CN | disclosed |