Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28470332 | 0.85 | MAPKAPK2 (0.49) | MAPKAPK2MAPTALDH1A1KMT2ATP53 | |
| SCHEMBL30148042 | 0.85 | MAPKAPK2 (0.49) | MAPKAPK2MAPTALDH1A1KMT2ATP53 | |
| SCHEMBL28471016 | 0.76 | MAPKAPK2 (0.51) | MAPKAPK2MAPTALDH1A1HTR2BKDM4E | |
| SCHEMBL30148069 | 0.76 | MAPKAPK2 (0.51) | MAPKAPK2MAPTALDH1A1HTR2BKDM4E | |
| SCHEMBL30148132 | 0.73 | MAPKAPK2 (0.55) | MAPKAPK2MAPTALDH1A1HTR2BKDM4E | |
| SCHEMBL28475885 | 0.73 | LMNA (0.48) | MAPTALDH1A1KDM4EKMT2ATP53 | |
| SCHEMBL2707877 | 0.67 | MAPKAPK2 (0.62) | MAPKAPK2MAPTALDH1A1HTR2BTP53 | |
| SCHEMBL9401140 | 0.67 | MAPKAPK2 (0.61) | MAPKAPK2MAPTALDH1A1HTR2BKMT2A | |
| SCHEMBL6237350 | 0.66 | MAPKAPK2 (0.55) | MAPKAPK2MAPTALDH1A1HTR2BKDM4E | |
| SCHEMBL8025885 | 0.65 | MAPKAPK2 (0.56) | MAPKAPK2MAPTALDH1A1HTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111675725-B | Tetrahydro-beta-carbaline dimer and preparation method and application thereof | 中国药科大学 | 2023-01-24 | — | — | CN | disclosed |