Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30140001 | 1.00 | CFD (0.64) | CFDCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL10217259 | 0.81 | CFD (0.59) | CFDCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL17023736 | 0.81 | CFD (0.59) | CFDCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL12480093 | 0.81 | CFD (0.59) | CFDCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL29781979 | 0.81 | CFD (0.59) | CFDCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL30682759 | 0.81 | CFD (0.42) | CFD | |
| SCHEMBL30682599 | 0.81 | CFD (0.42) | CFD | |
| SCHEMBL26951122 | 0.81 | CFD (0.42) | CFD | |
| SCHEMBL9618239 | 0.81 | PNMT (0.62) | CFDCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL26951121 | 0.81 | CFD (0.42) | CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266427-A1 | 4-(ARYL-METHYL-AMINO)-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |