⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477433 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL10416679 | 0.98 | ADRA2A (0.48) | — | |
| SCHEMBL3275986 | 0.81 | ADRA2A (0.50) | — | |
| SCHEMBL30384637 | 0.77 | — | — | |
| SCHEMBL9095841 | 0.77 | — | — | |
| SCHEMBL9095842 | 0.77 | — | — | |
| SCHEMBL8916413 | 0.77 | — | — | |
| SCHEMBL708434 | 0.77 | — | — | |
| Water SCHEMBL28118014 | 0.76 | ADRA2A (0.45) | — | |
| Fluoride SCHEMBL28035044 | 0.76 | ADRA2A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018021-B2 | Thiophene derivatives for the treatment of disorders caused by IgE | UCB Biopharma SRL (BE) | 2024-06-25 | — | — | US | disclosed |
| US-20220332709-A1 | Thiophene derivatives for the treatment of disorders caused by IgE | UCB Biopharma SRL (BE) | 2022-10-20 | — | — | US | disclosed |