SCHEMBL3275986

SCHEMBL3275986

C(=Nc1ccccn1)=Nc1ccccn1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 3/20 0.50
ADRA2B P18089 3/20 0.50
ADRA2C P18825 3/20 0.50
MAOA P21397 2/20 0.50
MAOB P27338 2/20 0.50
PLAU P00749 1/20 0.50
KDM4E B2RXH2 2/20 0.42
LMNA P02545 2/20 0.42
POLB P06746 2/20 0.42
CYP1A2 P05177 1/20 0.42
CCR1 P32246 1/20 0.42
CCR5 P51681 1/20 0.42
CCR8 P51685 1/20 0.42
METAP1 P53582 1/20 0.42
BLM P54132 1/20 0.42
HIF1A Q16665 1/20 0.42
DOHH Q9BU89 1/20 0.42
P4HTM Q9NXG6 1/20 0.42
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28410677 0.89 MAOA (0.57) ADRA2AADRA2BADRA2CMAOAMAOB
SCHEMBL11156195 0.82 ADRA2A (0.44) ADRA2AADRA2BADRA2CMAOAMAOB
SCHEMBL9095841 0.81
SCHEMBL8916413 0.81
SCHEMBL30148426 0.81
SCHEMBL708434 0.81
SCHEMBL30384637 0.81
SCHEMBL1477433 0.81
SCHEMBL9095842 0.81
Hydrochloric Acid SCHEMBL10416679 0.79 ADRA2A (0.48) ADRA2AADRA2BADRA2CMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2592120-B1 AQUEOUS INKJET INK, AND METHOD FOR FORMING INKJET IMAGE KONICA MINOLTA HOLDINGS INC (JP) 2017-08-02 EP disclosed
US-7695898-B2 Photothermographic material and image formation method FUJIFILM CORPORATION (JP) 2010-04-13 US disclosed
US-20090123881-A1 PHOTOTHERMOGRAPHIC MATERIAL AND IMAGE FORMATION METHOD FUJIFILM CORPORATION (JP) 2009-05-14 US disclosed
US-20030194660-A1 Heat developable light sensitive material and image forming method FUJI PHOTO FILM CO., LTD. (JP) 2003-10-16 US disclosed
US-20030138739-A1 Photothermographic material and image forming method FUJI PHOTO FILM CO., LTD. 2003-07-24 US disclosed
US-20030118954-A1 Photothermographic material and image formation method FUJIFILM CORPORATION (JP) 2003-06-26 US disclosed
US-5084304-A Heat resistant coating applied to a metal, a heat resistant material polymer such as a blend of a polyesterimide, a polyhydantoin, a polyamide, a polyamideimide copolymer and a polybismaleimide BASF LACKE & FARBEN AG (DE) 1992-01-28 US disclosed
EP-0079021-B1 PROCESS FOR PREPARING (THIO)HYDANTOINS BAYER AG (DE) 1986-03-05 EP disclosed
EP-0079020-B1 PROCESS FOR PREPARING HYDANTOINS BAYER AG (DE) 1986-02-05 EP disclosed
US-4465839-A CYCLIZATION OF CARBODIIMIDE, ACID ANHYDRIDE, AND AROMATIC ALCOHOL BAYER AKTIENGESELLSCHAFT (DE) 1984-08-14 US disclosed
US-4465840-A REACTING CARBODIIMIDE WITH HYDROXY- OR MERCAPTO-SUCCINIC DIESTER BAYER AKTIENGESELLSCHAFT (DE) 1984-08-14 US disclosed
EP-0079020-A2 Process for preparing hydantoins BAYER AG (DE) 1983-05-18 EP disclosed
EP-0079021-A2 Process for preparing (thio)hydantoins BAYER AG (DE) 1983-05-18 EP disclosed
US-4202786-A Peroxygen bleaching and compositions therefor FMC CORPORATION (US) 1980-05-13 US disclosed