Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17387588 | 0.86 | HSD17B10 (0.55) | CSF1RROCK1HSD17B10AAK1DGAT1 | |
| SCHEMBL136447 | 0.85 | CSF1R (0.41) | CSF1RROCK1HSD17B10AAK1DGAT1 | |
| SCHEMBL27159855 | 0.81 | ALDH1A1 (0.44) | CSF1RMEN1ALDH1A1KMT2ALIPG | |
| SCHEMBL30159430 | 0.80 | CSF1R (0.43) | CSF1RROCK1AAK1DGAT1HIF1A | |
| SCHEMBL12006791 | 0.80 | CSF1R (0.43) | CSF1RROCK1AAK1DGAT1HIF1A | |
| SCHEMBL21177199 | 0.78 | CSF1R (0.42) | CSF1RROCK1AAK1DGAT1HIF1A | |
| SCHEMBL27160080 | 0.78 | LPL (0.40) | CSF1RROCK1MEN1ALDH1A1KMT2A | |
| SCHEMBL1555488 | 0.78 | HTR2A (0.44) | CSF1RLIPGLPL | |
| SCHEMBL17939853 | 0.78 | PDE4D (0.42) | CSF1RROCK1AAK1DGAT1HIF1A | |
| SCHEMBL17939850 | 0.77 | AAK1 (0.42) | CSF1RROCK1POLBHSD17B10AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268209-A1 | DERIVATIVE HAVING PYRIMIDINE-FUSED CYCLIC STRUCTURE, AND USE THEREOF | 四川汇宇制药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |