Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.43 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.36 |
| ▸ | CDK2 | P24941 | 7/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.35 |
| ▸ | CDK9 | P50750 | 3/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CCNT2 | O60583 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30148784 | 0.91 | CDK1 (0.53) | CDK1CDK2CCNE2CCNE1CDK5 | |
| SCHEMBL30148806 | 0.83 | CDK1 (0.45) | CDK1EZH2ADORA3ADORA1CDK2 | |
| SCHEMBL30148802 | 0.82 | CTSL (0.46) | CDK1ADORA3ADORA1CDK2CCNE2 | |
| SCHEMBL30148812 | 0.81 | CDK1 (0.45) | CDK1ADORA3ADORA1CDK2CCNE2 | |
| SCHEMBL30148783 | 0.79 | CDK1 (0.45) | CDK1ADORA3ADORA1CDK2CCNE2 | |
| SCHEMBL30148801 | 0.79 | YTHDC1 (0.58) | ADORA3ADORA1ADORA2A | |
| SCHEMBL28523974 | 0.74 | CDK1 (0.57) | CDK1CDK2CCNE2CCNE1CDK5 | |
| SCHEMBL30148780 | 0.72 | CDK1 (0.55) | CDK1CDK2CCNE2CCNE1CDK5 | |
| SCHEMBL5196618 | 0.71 | CDK1 (0.52) | CDK1ADORA3ADORA1CDK2CDK5 | |
| SCHEMBL5192872 | 0.71 | CDK1 (0.79) | CDK1CDK2CCNE2CCNE1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903289-B | Purine-aminomethyl-pyridone derivative, preparation method and application thereof | 四川大学 | 2023-02-03 | — | — | CN | disclosed |