SCHEMBL30148899

SCHEMBL30148899

O=C(O)C1CC12CCCC2=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
HSD11B1 P28845 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2763653 0.94 HTT (0.32) TSHRHSD11B1
SCHEMBL5818626 0.77 LMNA (0.33) TSHR
SCHEMBL30170309 0.71 KDM1A (0.54) KDM1A
SCHEMBL30194202 0.71 KDM1A (0.54) KDM1A
SCHEMBL19041299 0.71 KDM1A (0.54) KDM1A
SCHEMBL30194273 0.71 KDM1A (0.54) KDM1A
SCHEMBL19041440 0.71 KDM1A (0.54) KDM1A
SCHEMBL19041432 0.71 KDM1A (0.54) KDM1A
SCHEMBL19030669 0.71 KDM1A (0.54) KDM1A
SCHEMBL3354448 0.69 KDM1A (0.44) KDM1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115521325-A Boronic acid derivatives 首药控股(北京)股份有限公司 2022-12-27 CN disclosed