Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.47 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.45 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30149287 | 0.99 | ALDH1A1 (0.47) | NPSR1TRPC4TRPC5KCNH2ALDH1A1 | |
| SCHEMBL30149483 | 0.98 | NPSR1 (0.48) | NPSR1TRPC4TRPC5KCNH2ALDH1A1 | |
| SCHEMBL30149481 | 0.96 | NPSR1 (0.47) | NPSR1TRPC4TRPC5KCNH2ALDH1A1 | |
| SCHEMBL30149504 | 0.93 | NPSR1 (0.49) | NPSR1TRPC4TRPC5KCNH2ALDH1A1 | |
| SCHEMBL30149487 | 0.93 | TRPC5 (0.55) | TRPC4TRPC5KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30149383 | 0.92 | TRPC5 (0.55) | TRPC4TRPC5KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30149453 | 0.91 | TRPC5 (0.45) | NPSR1TRPC4TRPC5KCNH2ALDH1A1 | |
| SCHEMBL30149537 | 0.91 | TRPC5 (0.55) | TRPC4TRPC5KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30149402 | 0.90 | TRPC5 (0.46) | NPSR1TRPC4TRPC5KCNH2ALDH1A1 | |
| SCHEMBL30149443 | 0.90 | TRPC4 (0.46) | NPSR1TRPC4TRPC5KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115636831-B | Fused pyrimidinediones, their use and pharmaceutical compositions | 中国药科大学 | 2024-11-08 | — | — | CN | disclosed |
| CN-115636831-A | Fused pyrimidinediones, their use and pharmaceutical compositions | 中国药科大学 | 2023-01-24 | — | — | CN | disclosed |