Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 5/20 | 0.56 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30149505 | 0.85 | TRPC5 (0.57) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL30149367 | 0.85 | TRPC5 (0.57) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL30149537 | 0.84 | TRPC5 (0.55) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL30149487 | 0.84 | TRPC5 (0.55) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL30149323 | 0.84 | TRPC5 (0.56) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL30149383 | 0.84 | TRPC5 (0.55) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL30149376 | 0.84 | TRPC5 (0.55) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL30149527 | 0.83 | TRPC5 (0.60) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL30149467 | 0.83 | TRPC5 (0.56) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL30149460 | 0.83 | TRPC5 (0.54) | TRPC5TRPC4KCNH2TP53TRPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115636831-B | Fused pyrimidinediones, their use and pharmaceutical compositions | 中国药科大学 | 2024-11-08 | — | — | CN | disclosed |
| CN-115636831-A | Fused pyrimidinediones, their use and pharmaceutical compositions | 中国药科大学 | 2023-01-24 | — | — | CN | disclosed |