Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009780 | 0.90 | MGLL (0.47) | IDO1PTGDR2FFAR1FFAR4FFAR2 | |
| SCHEMBL27551256 | 0.88 | IDO1 (0.50) | IDO1 | |
| SCHEMBL584750 | 0.87 | FFAR1 (0.54) | IDO1PTGDR2FFAR1FFAR4 | |
| SCHEMBL5208242 | 0.85 | IDO1 (0.51) | IDO1 | |
| SCHEMBL34475543 | 0.83 | CES2 (0.50) | PTGDR2FFAR1FFAR4FFAR2KMO | |
| SCHEMBL1207452 | 0.83 | CES2 (0.50) | PTGDR2FFAR1FFAR4FFAR2KMO | |
| SCHEMBL2393327 | 0.83 | POLB (0.54) | PTGDR2FFAR1FFAR4FFAR2KMO | |
| Trifluoroacetic Acid SCHEMBL30151180 | 0.83 | IDO1 (0.43) | IDO1PTGDR2FFAR1FFAR4FFAR2 | |
| SCHEMBL892902 | 0.83 | IDO1 (0.51) | IDO1PTGDR2FFAR4 | |
| SCHEMBL30120834 | 0.83 | IDO1 (0.51) | IDO1PTGDR2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551846-B | 1,4,5, 6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2024-03-08 | — | — | CN | claimed |
| WO-2023085396-A1 | PHARMACEUTICAL COMPOSITION FOR PROVIDING TREATMENT FOR OR PREVENTING ALPORT SYNDROME | ＵＢＥ株式会社 | 2023-05-19 | — | — | WO | claimed |
| CN-115551846-A | 1,4,5,6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2022-12-30 | — | — | CN | claimed |
| CN-115551846-B | 1,4,5, 6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2024-03-08 | — | — | CN | disclosed |
| WO-2023085396-A1 | PHARMACEUTICAL COMPOSITION FOR PROVIDING TREATMENT FOR OR PREVENTING ALPORT SYNDROME | ＵＢＥ株式会社 | 2023-05-19 | — | — | WO | disclosed |
| CN-115551846-A | 1,4,5,6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2022-12-30 | — | — | CN | disclosed |