Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1567847 | 1.00 | NR3C2 (0.51) | NR3C2FFAR1FFAR4EPHX2KEAP1 | |
| SCHEMBL28292529 | 0.90 | CYP1A2 (0.50) | NR3C2FFAR1FFAR4 | |
| SCHEMBL27841065 | 0.88 | NR3C2 (0.52) | NR3C2 | |
| SCHEMBL585165 | 0.87 | FFAR4 (0.51) | FFAR1FFAR4EPHX2 | |
| Trifluoroacetic Acid SCHEMBL30151176 | 0.83 | NR3C2 (0.46) | NR3C2FFAR1FFAR4 | |
| SCHEMBL30120926 | 0.83 | RXRA (0.57) | NR3C2 | |
| SCHEMBL308545 | 0.83 | RXRA (0.57) | NR3C2 | |
| SCHEMBL22630207 | 0.82 | FFAR1 (0.56) | FFAR1FFAR4EPHX2 | |
| SCHEMBL3534750 | 0.81 | FFAR1 (0.50) | FFAR1FFAR4EPHX2KEAP1 | |
| SCHEMBL586063 | 0.80 | FFAR1 (0.58) | FFAR1FFAR4KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551846-B | 1,4,5, 6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2024-03-08 | — | — | CN | claimed |
| WO-2023085396-A1 | PHARMACEUTICAL COMPOSITION FOR PROVIDING TREATMENT FOR OR PREVENTING ALPORT SYNDROME | ＵＢＥ株式会社 | 2023-05-19 | — | — | WO | claimed |
| CN-115551846-A | 1,4,5,6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2022-12-30 | — | — | CN | claimed |
| CN-115551846-B | 1,4,5, 6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2024-03-08 | — | — | CN | disclosed |
| WO-2023085396-A1 | PHARMACEUTICAL COMPOSITION FOR PROVIDING TREATMENT FOR OR PREVENTING ALPORT SYNDROME | ＵＢＥ株式会社 | 2023-05-19 | — | — | WO | disclosed |
| CN-115551846-A | 1,4,5,6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2022-12-30 | — | — | CN | disclosed |