Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30151178 | 0.83 | FFAR4 (0.50) | EPHX2FFAR4P2RX7GAAPOLB | |
| SCHEMBL21015416 | 0.82 | EPHX2 (0.51) | EPHX2FFAR4GAAPOLBFFAR1 | |
| SCHEMBL9494344 | 0.81 | EPHX2 (0.43) | EPHX2GAAPOLBTDP1KDM4E | |
| SCHEMBL31645683 | 0.80 | P2RX7 (0.47) | EPHX2P2RX7KDM4EPTGS2CTSS | |
| SCHEMBL15287109 | 0.80 | P2RX7 (0.44) | EPHX2P2RX7GAAPOLBTDP1 | |
| SCHEMBL27643599 | 0.78 | FFAR4 (0.43) | EPHX2FFAR4P2RX7GAAPOLB | |
| SCHEMBL29174148 | 0.77 | PTGER1 (0.44) | FFAR4FFAR1TDP1KDM4EALDH1A1 | |
| SCHEMBL20341728 | 0.76 | IAPP (0.46) | POLBTDP1KDM4EALDH1A1HTT | |
| SCHEMBL12955273 | 0.76 | CYP4F2 (0.43) | GAAPOLBTDP1KDM4EALDH1A1 | |
| SCHEMBL2031772 | 0.75 | SMN1; SMN2 (0.46) | EPHX2P2RX7GAAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551846-A | 1,4,5,6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2022-12-30 | — | — | CN | disclosed |